In experimental models of cognitive impairment, astaxanthin treatment has been shown to enhance hippocampal LTP while preventing stress- or toxin-induced synaptic weakening, suggesting preservation of activity-dependent synaptic signaling
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Oxidative stress then accelerates the aggregation of -synuclein which subsequently binds and sequesters available GSH, creating a destructive feedback loop of protein misfolding and antioxidant loss (Hoepken et al., 2007)
Crit Rev Biochem Mol Biol 30:521600
Thus, as Joe Rogans experience suggests, these supplements may help alleviate stress and promote quality sleep
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